Studies Indicate That Individuals With This Blood Type Have a Higher Likelihood of Living to 100

Reaching 100 was once rare, but today it’s becoming increasingly common. Still, researchers wondered whether routine blood tests taken years earlier could offer clues about who reaches such exceptional longevity. A Swedish study followed tens of thousands of people, examining common biomarkers like glucose and cholesterol to see how they related to living past 90 or even 100.

The study focused on whether simple lab results collected at midlife could predict exceptional longevity. Participants who eventually reached 100 were compared with peers who did not, all tested at about the same age. The research examined markers of metabolism, kidney and liver function, iron status, and inflammation. With follow-up lasting up to 35 years, the design allowed strong long-term conclusions.

Researchers used the AMORIS cohort, which includes extensive lab data from Stockholm County. This study analyzed 44,636 participants born between 1893 and 1920. Over time, 1,224 people reached age 100, the majority of them women. Swedish national registers allowed accurate tracking of diseases and deaths, and statistical methods helped identify meaningful patterns.

Twelve routine markers were analyzed, including glucose, total cholesterol, creatinine, several liver enzymes, albumin, iron, total iron-binding capacity, and uric acid. The authors later clarified that low cholesterol—not high cholesterol—was linked with reduced odds of reaching 100. Very low iron also lowered the odds.

Glucose showed one of the clearest patterns: people in the highest ranges had the lowest odds of becoming centenarians. This aligns with long-established links between high blood sugar, vascular disease, and aging.

Kidney and liver markers also mattered. High creatinine and elevated liver enzymes were tied to lower odds of exceptional longevity, suggesting that long-term organ strain may influence lifespan.

Uric acid showed a strong trend as well: the lowest levels were associated with higher chances of reaching 100. Because uric acid relates to inflammation, this may hint at lower chronic inflammatory burden in long-lived individuals.

Overall, the study suggests that extremes—very high or very low lab values—tend to reduce the odds of reaching 100. While no test predicts an individual’s future, these patterns highlight the value of balanced metabolic and organ health over time.